Cresce lentamente como uma massa firme e indolor na bochecha. It is the second most common benign parotid gland tumor and accounts for 4% to 25% of all salivary gland tumors. Kontrastverstarkte sonografische, perfusionsdynamische. Surgical treatment strategy in warthin tumor of the parotid. Warthin tumor genetic and rare diseases information. It is a slowgrowing lesion that is generally located in the superficial lobe of the parotid gland 90% and is usually asymptomatic. You may purchase original highresolution image without pathpedia logo using our automated system that grants singleuser and multiuser, nonroyaltybased. Ideal sources for wikipedia s health content are defined in the guideline wikipedia. Almost all warthin s tumors occur in the parotid gland and account for 5 percent of parotid tumors. This type of tumor is benign, which means it isnt cancerous. Furthermore, signs and symptoms of warthins tumor may vary on an individual basis for each patient.
Warthins tumor is a relatively rare and generally benign neoformation whose incidence is second only to the pleomorphic adenoma. The tumor is well demarcated, grey yellow in color. Occasional features are cilia, squamous metaplasia associated with infarctlike necrosis, mast cells, dendritic cells, mucin secreting cells, sebaceous cells. In addition, this tumor demonstrates areas of degeneration and necrosis yellowish foci. Warthin s tumor type of benign tumor of the salivary glands. With a slight white male predominance, presentation normally occurs in the 6th to 7th decades as an asymptomatic, slowgrowing 1. Warthins tumour of the larynx is an unusual finding. It makes up 14% to 30% of parotid tumors1 and is well known among otolaryngologists. Pode tambem ser encontrado na literatura cientifica pelos nomes cistoadenoma papilifero linfomatoso, cistoadenolinfoma e adenolinfoma. Discussion warthin s tumor is a benign neoplasm of sali vary glands, first described by aldred warthin in. Characteristic findings of warthins tumor on gross pathology are. Warthins tumour papillary cystadenoma lymphomatosum pcl constitutes a minority of salivary gland neoplasms and it is a monomorphic adenoma which primarily involves the parotid gland. Warthin tumor is the second most common type of benign parotid tumor, which develop as bilateral in both the side or multifocal means multiple origins benign parotid tumor. Sep 20, 2014 warthin s tumour papillary cystadenoma lymphomatosum pcl constitutes a minority of salivary gland neoplasms and it is a monomorphic adenoma which primarily involves the parotid gland.
Mar 12, 2015 gross appearance of warthin tumor of parotid gland. The size is variable, from a few millimeters to centimeters, averaging 2 to 4 cm in diameter, with a preferred location in the lower pole of. Sebek, rafael valenzuela, immunohistochemistry of warthins tumor, american journal of clinical pathology, volume 74, issue 6, 1 december 1980. If you have problems viewing pdf files, download the latest version of adobe reader. Warthin tumour is a relative common benign tumour of the parotid gland. Warthin s tumour shows multiple cysts that have numerous papillations covered by bilayered columnar and basaloid oncocytic epithelium. The case described above is typical of warthin tumor. Warthins tumor, also known as papillary cystadenoma lymphomatosum, is a benign cystic tumor of the salivary glands containing abundant lymphocytes and germinal centers lymph nodelike stroma. The patients age, smoking history, lack of symptoms, and delay in presentation are all typical. The presence of multiple large cystic spaces is characteristic of this lesion.
The almost total lack of recurrence and malignant transformation of this tumor, similar to the situation in congenital lateral cervical cysts, further supports this view. Uniquely, among benign lesions of the parotid gland, it can be seen bilaterally in 710% of cases. The wt shows male predominance, with the ratio of male patients to female patients ranging from 1. Warthin tumors were differentiated from other types of tumors with 67%. The warthin tumor wt is a common benign parotid gland tumor that accounts for approximately 1530% of parotid tumors. Pleomorphic adenoma is the most common tumor of the parotid gland overall. The trip database provides clinical publications about evidence.
Warthin tumor papillary cystadenoma lymphomatosum, adenolymphoma is a benign neoplasm from salivary glands and is almost restricted to the parotid gland and the periparotid lymph nodes. Ing taun 1910, albrecht arzt uga maringi laporan babagan tumor saka gulu nginggil ingkang diudhari dadi jaringan ingkang boten wonten panuture sajeroning. A read is counted each time someone views a publication summary such as the title, abstract, and list of authors, clicks on a figure, or views or downloads the fulltext. A warthins tumor, also referred to as papillary cystadenoma lymphomatosum, is a type of benign, or noncancerous, tumor that affects the salivary glands. First described in 1895, this tumor was called papillary cystadenoma lymphomatosum by warthin in 1929. Warthins tumor is removed surgically as a last option of treatment when medications are of no use. The adenolymphoma is a cystic tumor containing a mucoid substance. Warthin tumor, also known as papillary cystadenoma lymphomatosum,2 is a fairly common tumor. Only a few studies describing the sonographic features of pleomorphic adenomas and warthins tumors have been published, and most of. Simultanes auftreten eines zystadenolymphoms warthintumor in. The patient may complain of tinnitus, pain in the ear and deafness. It has 23 synonyms in the english language due to different opinions regarding origin of the tumor. For language access assistance, contact the ncats public information officer. Differentiation of pleomorphic adenoma and warthins tumor.
It is named for pathologist aldred scott warthin, who described two cases in 1929. Very rarely, warthins tumor can also mimic malignant or metastatic disease by presenting within cervical lymph nodes. Warthins tumor is an adenoma composed of bilayered columnar and basaloid oncocytic epithelium that forms multiple cysts with numerous papillae, accompanied by a proliferation of folliclecontaining lymphoid tissue. Warthin s tumour papillary cystadenoma lymphomatosum pcl constitutes a minority of salivary gland neoplasms and it is a monomorphic adenoma which primarily involves the parotid gland. Discussion warthins tumor is a benign neoplasm of sali vary glands, first described by aldred warthin in.
Warthin tumor is typically tannish brown, often with cystic spaces. Warthin tumor papillary cystadenoma lymphomatosum reported by warthin since 1929, is rare and benign salivary gland tumor that occurs almost exclusively in the parotid. This signs and symptoms information for warthins tumor has been gathered from various sources, may not be fully accurate, and may not be the full list of warthins tumor signs or warthins tumor symptoms. Warthin tumors may increase in size over time, but few become cancerous. Gross appearance of warthin tumor of parotid gland.
Warthin tumor treatment, prognosis, causes, diagnosis, symptoms. The tumor usually grows very slowly and is painless. The tumor is usually asymptomatic and may be associated with varying degrees of pain not necessarily an indication of malignant transformation in the tumour. In surgery, an incision is made on the bulged out mass of tumor. Warthin tumor is a benign tumor of the salivary gland. Warthins tumor symptoms, causes, treatment, surgery. Most cases of reported malignancy can be attributed to a second tumor in association with warthins tumor. Warthins tumor cystadenolymphoma of salivary glands. Etiology several studies showed that a significant number of patients suffering from warthins tumor are smokers, in contrast to patients with other salivary gland tumors. A warthins tumor is a growth that forms in a persons salivary glands. The first symptom is usually a painless, slowgrowing bump in front of the ear, on the bottom of the mouth, or under the chin.
Common symptoms of a warthins tumor include swelling in the neck that may or may not cause tenderness or discomfort, ringing in the ears, and impaired hearing. Warthins tumor accounts for almost 425% of all kinds of tumors occurring in salivary glands as well as it is known as the second most. It is an interesting tumor in that it has significant amount of mitochondria, which accounts for its high uptake in technetium99 scanning. Warthins tumor is the second most common tumor of the parotid gland and the most common bilateral tumor.
The first two cases of warthins tumor were reported in 1929 by a pathologist aldred scott warthin and so the disease was named after his name. Warthins tumor is the second most common benign lesion of the parotid gland. Media in category warthins tumor this category contains only the following file. In addition, a polyclonal growth of the epithelial components of the tumor could be detected. It is most commonly encountered in male smokers in the fifth to seventh decades of life. Its etiopathogenesis has been associated with tobacco smoke. Case report an unusual warthins tumor arising from minor. Encapsulated, lobulated, pale gray surface, multicystic with mucinous serous secretion, 10 15% multifocal bilateral. The surgical removal of warthins tumor is the widely used treatment of warthins tumor. It represents 7% of all salivary gland tumors, and it. Immunohistochemistry of warthins tumor american journal. Warthins tumors occur bilateral in 710%, whereas a. Warthin tumor genetic and rare diseases information center. Warthin tumor morphological study of the stromal compartment.
The patient was followed up for six months without any signs of recurrence of the lesion. May undergo hemorrhagic infarction, particularly after fine needle aspiration. Warthin tumor is the second most common benign salivary gland tumor and characteristically presents in the lower portion of the lateral lobe of the parotid gland. While some benign tumors may eventually develop cancerous cells, this occurrence is extremely unlikely with warthins tumors. Warthins tumour shows multiple cysts that have numerous papillations covered by bilayered columnar and basaloid oncocytic epithelium. Warthin s tumor may therefore also be classified in the group of tumor like lesions, since both the epithelial and lymphoid tumor components are polyclonal in origin. Cystadenolymphomas warthins tumors are the second most frequent lesions of the parotid gland.